Best Restaurants in Winston-Salem NC

Introduction

Winston-Salem, North Carolina, has evolved into one of the Piedmont Triad’s most exciting dining destinations. Blending rich Moravian heritage with modern Southern cuisine, the city offers everything from chef-driven tasting menus to casual neighborhood favorites. Whether you are planning a weekend getaway or scouting new local spots, the following guide highlights 10 of the best restaurants in Winston-Salem, NC. Each selection emphasizes quality, consistency, and a memorable guest experience, making this list a useful starting point for exploring the city’s dynamic food scene.

The Katharine Brasserie and Bar

Located inside the iconic Kimpton Cardinal Hotel in the former R.J. Reynolds building, The Katharine Brasserie & Bar brings a refined French brasserie experience to downtown Winston-Salem. The menu balances classic French techniques with local ingredients, featuring dishes like steak frites, fresh seafood, and expertly prepared seasonal vegetables. The ambiance, with its marble-topped bar and Art Deco details, is ideal for business dinners, date nights, or pre-theater cocktails. Conveniently situated near downtown offices, cultural venues, and hotels, The Katharine is a strong choice for visitors seeking elevated yet approachable cuisine in the city center.

Spring House Restaurant Kitchen and Bar

Set in a beautifully restored 1920s mansion, Spring House Restaurant, Kitchen & Bar showcases modern Southern cuisine with a strong emphasis on local and seasonal ingredients. The menu changes frequently, offering inventive takes on regional favorites such as shrimp and grits, braised meats, and farm-fresh salads. Multiple dining rooms, a cozy bar area, and outdoor seating create an intimate yet flexible setting that works well for special occasions, corporate gatherings, or relaxed dinners with friends. With its combination of historic charm and progressive culinary vision, Spring House has become a cornerstone of Winston-Salem’s fine-dining landscape.

The Honey Pot

For a creative, chef-driven experience in the heart of downtown, The Honey Pot focuses on inventive seasonal dishes that highlight regional produce and sustainably sourced meats. Diners can expect a menu that evolves regularly, with small plates, shareable dishes, and thoughtful entrées that encourage exploration. The intimate, stylish interior and attentive service make The Honey Pot especially popular among food enthusiasts looking for something beyond traditional Southern fare. Because of its popularity and relatively small dining room, reservations are recommended, particularly on weekends and during local events.

Mojito Latin Soul Food

Blending Cuban, Caribbean, and Latin American flavors, Mojito Latin Soul Food brings vibrant dishes and lively hospitality to Winston-Salem’s dining mix. Signature plates include slow-roasted pork, Cuban sandwiches, empanadas, and plantain-based sides, all prepared with a focus on bold seasonings and authentic techniques. The colorful, relaxed atmosphere makes it a popular spot for groups and families, while the full bar, featuring mojitos and other classic cocktails, contributes to its appeal as a social destination. For visitors interested in exploring global cuisines within the city, Mojito Latin Soul Food provides a flavorful and memorable option.

Mission Pizza Napoletana

Recognized as one of the most serious pizza destinations in the region, Mission Pizza Napoletana specializes in wood-fired, Neapolitan-style pies made with naturally leavened dough and carefully sourced ingredients. The menu features traditional combinations as well as creative seasonal specials, complemented by a curated selection of craft beers and wines. The casual, modern space places the open kitchen and impressive pizza oven at center stage, allowing guests to watch the process from dough to table. For both locals and travelers seeking top-tier pizza in Winston-Salem, Mission Pizza Napoletana consistently stands out.

Mozelles Fresh Southern Bistro

Situated in the historic West End neighborhood, Mozelle’s Fresh Southern Bistro delivers a polished yet welcoming take on Southern comfort food. The restaurant is known for dishes like tomato pie, meatloaf, fried chicken, and seasonal vegetable sides, all prepared with high-quality ingredients and careful attention to detail. A cozy interior and popular sidewalk seating create a neighborhood bistro feel that appeals to both longtime residents and first-time visitors. Because of its reputation and relatively limited seating, Mozelle’s often fills quickly, making advance planning helpful, especially for weekend brunch and dinner.

Foothills Brewpub

Beer enthusiasts will appreciate Foothills Brewpub, the original downtown location of Winston-Salem’s renowned Foothills Brewing. In addition to a wide range of award-winning craft beers, the brewpub offers a robust menu of burgers, sandwiches, wings, and hearty entrées that pair naturally with its rotating taps. The lively, casual atmosphere makes it well-suited for groups, game days, and relaxed evenings out. With its central location, extensive beer list, and consistently satisfying food, Foothills Brewpub is a reliable choice for those wanting to experience the city’s craft beer culture alongside a solid meal.

Caminos Mexican Grill

For fresh, contemporary Mexican cuisine, Caminos Mexican Grill offers a menu that goes beyond standard combination plates to feature tacos, fajitas, seafood dishes, and creative house specialties. Emphasis on quality ingredients, colorful presentation, and balanced flavors sets Caminos apart in a competitive category. The inviting dining room and family-friendly environment make it a practical option for both casual lunches and relaxed dinners. With attentive service and a range of margaritas and cocktails, Caminos Mexican Grill has become a preferred spot for those seeking authentic, flavor-forward Mexican fare in Winston-Salem.

Six Hundred Degrees

Located in the historic Bailey Power Plant development, Six Hundred Degrees delivers a sophisticated, fire-focused menu featuring wood-grilled steaks, seafood, and shareable plates. The restaurant’s name reflects its commitment to high-heat cooking techniques that intensify flavors and textures. A dramatic interior with exposed industrial details, along with a thoughtfully curated bar program, helps create a memorable downtown dining experience. Ideal for business dinners, celebrations, and nights out in the Innovation Quarter, Six Hundred Degrees provides a modern contrast to Winston-Salem’s more traditional eateries.

Roosters A Noble Grille

Part of the locally respected Noble Food & Pursuits group, Roosters: A Noble Grille emphasizes farm-to-table cooking with a Southern and European influence. The menu features wood-fired meats, fresh seafood, seasonal vegetables, and artisan breads, all prepared with a commitment to sustainability and regional sourcing. A warm, upscale-casual interior and polished service make Roosters an excellent choice for business meals, special occasions, and date nights. Its location in the Buena Vista area, just minutes from downtown, offers convenient access for both locals and visitors.

Conclusion

From elegant brasseries and historic mansions to inventive pizzerias and vibrant Latin and Mexican kitchens, Winston-Salem’s restaurant scene reflects the city’s blend of tradition and innovation. Whether you are searching for a refined tasting experience, a family-friendly neighborhood spot, or a casual brewpub, these 10 restaurants represent some of the best dining options in Winston-Salem, NC. By exploring this diverse group of establishments, diners can gain a deeper appreciation for the city’s culinary identity and the talented chefs and restaurateurs who continue to shape it.